Benzyl-α-GalNAc
Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (e.g. pancreatic cancer) by inhibiting O-glycosylation[1][2][3].
Product Specifications
CAS Number
3554-93-6
UNSPSC
12352005
Target
Glycosyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/o-glycosylation-in-1.html
Concentration
10mM
Purity
99.93
Solubility
DMSO : ≥ 100 mg/mL|H2O : 7 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@@H]([C@H]([C@@H](CO)O1)O)[C@@H](NC(C)=O)[C@H]1OCC2=CC=CC=C2
Molecular Formula
C15H21NO6
Molecular Weight
311.33
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD45RO (UCHL-1), CF488A conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF647 conjugate, 0.1mg/mL
MUC18 / Mucin 18 / CD146 (OJ79c), CF740 conjugate, 0.1mg/mL
CD44 Standard (DF1485), CF405S conjugate, 0.1mg/mL
