IL-10, human recombinant

IL-10 (Interleukin-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 18.6 kDa protein containing 161 amino acid residues. It shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed-type hypersensitivity response, and stimulation of the Th2 cell response which results in elevated antibody production.