Biphenylindanone A

Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1].

Product Specifications

CAS Number

[866823-73-6]

Product Name Alternative

BINA

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/biphenylindanone-a.html

Purity

99.12

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC=CC(COC3=CC4=C(C(C(C5CCCC5)C4)=O)C(C)=C3C)=C2)C=C1)O

Molecular Formula

C30H30O4

Molecular Weight

454.56

Precautions

H302, H315, H319, H335

References & Citations

[1]Rowe BA, et al. Transposition of three amino acids transforms the human metabotropic glutamate receptor (mGluR) -3-positive allosteric modulation site to mGluR2, and additional characterization of the mGluR2-positive allosteric modulation site. J Pharmacol Exp Ther. 2008 Jul;326 (1) :240-51.