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Kinetin riboside

Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM.

Product Specifications

CAS Number

[4338-47-0]

Product Name Alternative

N6-Furfuryladenosine

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Kinetin_riboside.html

Purity

99.88

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)O1

Molecular Formula

C15H17N5O5

Molecular Weight

347.33

Precautions

H302, H315, H320, H335

References & Citations

[1]Rajabi M, et al. Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line. Nucleosides Nucleotides Nucleic Acids. 2012;31 (6) :474-81.|[2]Choi BH, et al. Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells. Cancer Lett. 2008 Mar 8;261 (1) :37-45.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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