Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Rhapontigenin

Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50 = 400 nM) . Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively[1].

Product Specifications

CAS Number

500-65-2

UNSPSC

12352005

Target

Bacterial; Cytochrome P450; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rhapontigenin.html

Purity

99.66

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC(/C=C/C2=CC=C(OC)C(O)=C2)=CC(O)=C1

Molecular Formula

C15H14O4

Molecular Weight

258.27

References & Citations

[1]Roupe KA, et al. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies.J Pharm Pharm Sci. 2005 Aug 22;8 (3) :374-86.|[2]Yeh YH, et al. Rhapontigenin inhibits TGF-β-mediated epithelial‑mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation.Oncol Rep. 2016 May;35 (5) :2887-95.|[3]Park EK, et al. Antithrombotic and antiallergic activities of rhaponticin from Rhei Rhizoma are activated by human intestinal bacteria.Arch Pharm Res. 2002 Aug;25 (4) :528-33.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

CYP1

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Neurocan Antibody
RC-16256-01 50 μL

Recombinant Neurocan Antibody

Sign In for Pricing
View Details
Recombinant Neurocan Antibody
RC-16256-02 100 µL

Recombinant Neurocan Antibody

Sign In for Pricing
View Details
Recombinant Neurocan Antibody
RC-16256-03 1 mL

Recombinant Neurocan Antibody

Sign In for Pricing
View Details
Vapor Pressure Tester (Reid Method) BPTL-264
BPTL-264 1 Unit

Vapor Pressure Tester (Reid Method) BPTL-264

Sign In for Pricing
View Details
Magnesium Bromide
TRC-M110385-5G 5 g

Magnesium Bromide

Sign In for Pricing
View Details
Zfp41 (NM_011759) Mouse Tagged ORF Clone
MG201976 10 µg

Zfp41 (NM_011759) Mouse Tagged ORF Clone

Sign In for Pricing
View Details