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LSN-2814617

LSN-2814617 is a potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). It acts as a potent and selective potentiator of human and rat mGlu₅ receptors in vitro, displaying curve shift ratios of two to three fold in the concentration-response relationship to glutamate or the glutamate receptor agonist, DHPG, with no detectable intrinsic agonist properties.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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