K02288
A potent and selective inhibitor of type I bone morphogenic protein (BMP) receptors (IC₅₀ values are 1.1, 1.8, 6.4, 34.4, 220, 302 and 321 nM for ALK2, ALK1, ALK6, ALK3, ActRIIA, ALK4 and ALK5 respectively). K02288 can prevent BMP4-induced SMAD1/5/8 pathway activation in vitro (IC₅₀ = 100 nM) without affecting TGF-β signaling.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months
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