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HFI-142

HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 2.01 μM[1].

Product Specifications

CAS Number

332164-34-8

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Aminopeptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hfi-142.html

Purity

99.55

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CCOC(C1=C(N)OC2=CC(O)=CC=C2C1C3=CN=CC=C3)=O

Molecular Formula

C17H16N2O4

Molecular Weight

312.32

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78 (4) :600-7.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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