HFI-142
HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 2.01 μM[1].
Product Specifications
CAS Number
332164-34-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hfi-142.html
Purity
99.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CCOC(C1=C(N)OC2=CC(O)=CC=C2C1C3=CN=CC=C3)=O
Molecular Formula
C17H16N2O4
Molecular Weight
312.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78 (4) :600-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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