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BMS-986158

BMS-986158 is a potent bromodomain (BRD) and extra-terminal domain (BET) family inhibitor.  BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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