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PF-8380

PF-8380 is a potent and specific inhibitor of Autotaxin (ATX) (IC₅₀ = 2.8 nM). Modulates lysophosphatidic acid (LPA) levels in vivo and in vitro by directly inhibiting autotaxin. Autotaxin (ATX) is a secreted enzyme having lysophospholipase D activity.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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