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PRL-3 Inhibitor

P0108 is a potent inhibitor of phosphatase of regenerating liver-3 (PRL-3) (IC₅₀ = 0.9 μM). It reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model. Sensitizes PRL-3-expressing cancer cells to chemotherapeutics. Inhibits dephosphorylation of tyrosine-783 of integrin β1 in BGC823 and SW480 cells.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20°C

Shelf Life

36 months

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