Oxaloacetic acid (Standard)

Oxaloacetic acid (Standard) is the analytical standard of Oxaloacetic acid. This product is intended for research and analytical applications. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function[1][2][3].

Product Specifications

CAS Number

[328-42-7]

Product Name Alternative

2-Oxosuccinic acid (Standard)

UNSPSC

12352211

Hazard Statement

H319, H402

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/oxaloacetic-acid-standard.html

Purity

99.50

Smiles

O=C(O)C(CC(O)=O)=O

Molecular Formula

C4H4O5

Molecular Weight

132.07

Precautions

H319, H402

References & Citations

[1]F. L. Breusch. The fate of oxaloacetic acid in different organs. Biochem J. 1939 Nov; 33 (11) : 1757-1770.|[2]Brian D Fink, et al. Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem. 2018 Dec 21;293 (51) :19932-19941.|[3]Li W, et al. Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction. Front Pharmacol. 2022 Oct 13;13:1029775.