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BAR-501

BAR-501 is a selective GPBAR1 agonist devoid of any FXR agonistic activity. It effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1, with an EC₅₀ of 1 μM. Exposure of GLUTAg cells to BAR501 (10 μM) increases the expression of GLP-1 mRNA by 2.5 folds.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20°C

Shelf Life

36 months

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