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L-838,417

L-838, 417 is a subtype-selective GABAA receptor partial agonist. It selectively binds to α1, α2, α3 and α5 subunits (Kivalues are 0.79, 0.67, 0.67 and 2.25 nM respectively) but displays no efficacy at α1 (α1-sparing). Exhibits non-sedative anxiolytic, antinociceptive and anti-inflammatory activity in vivo.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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