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EW-7197

EW-7197 is a potent ALK5 (TGF-β Type I receptor) inhibitor that displays anti metastatic activity in vivo. In vivo mice experiments show EW-7197 repeals TGF- β1 induced tumor cell migration and invasion inhibiting breast cancer metastasis to the lung. It prolongs the life span of BALB/c4T1 mice by inhibiting metastasis and enhancing the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotropic grafted mice.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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