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GW-441756

GW-441756 is potent and specific inhibitor of Trk A (tropomyosin-related kinase A) tyrosine kinase (IC₅₀ = 2 nM). This inhibition of TrkA reduces cell proliferation and enhances the effects of chemotherapeutic agents in sarcoma. GW-441756 displays >100-fold selectivity over a range of other kinases.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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