SW-044248
SW-044248 is a selective Topoisomerase I inhibitor. It is extremely potent and selectively toxic to NSCLC killing ~15% of a 74 NSCLC cell lines. It was not toxic to immortalized human bronchial cell lines. The intense transcriptional response to SW-044248 in HCC4017 cells significantly correlates to topoisomerase-I inhibition and not topoisomerase-II.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months
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