Homoharringtonine
Product Specifications
UNSPSC Description
Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.
Target Antigen
STAT
Type
Natural Products
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Homoharringtonine.html
Solubility
DMSO : ≥ 50 mg/mL|H2O : 1.4 mg/mL (ultrasonic)
Smiles
[H][C@@]12[C@](CCC3)(C=C(OC)[C@]2(OC([C@](CCCC(O)(C)C)(O)CC(OC)=O)=O)[H])N3CCC4=CC5=C(OCO5)C=C14
Molecular Weight
545.62
References & Citations
[1]Cao W, et al. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Sci Rep. 2015 Jul 13;5:8477
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14944/Homoharringtonine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14944/Homoharringtonine-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
26833-87-4
Available Sizes
Curated Selection
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