IC261
IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC₅₀ = ~1 µM for CK1δ and CK1ɛ and 16 µM for CK1α). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC261, at 1 µM, inhibits cytokinesis in primary mouse embryo fibroblasts. IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
QUEB15X36YPA 100 Pieces/Case:100 Pieces/ PACKS:1 PACKS/CASE
QuEChERS Extraction PouchAOAC 2007.01PSA/GCB Clean-up tube: 1200mg MgSO4 400mg PSA 400mg GCB
Sign In for Pricing
View Details 
