Question 1

What is the catalog number for GSK-4112?

Accepted Answer

The catalog number for GSK-4112 is 9663-5.

Question 2

Is GSK-4112 in stock?

Accepted Answer

GSK-4112 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is GSK-4112 used for?

Accepted Answer

GSK-4112 is a selective agonist for REV-ERBα (EC₅₀ = 0.4 μM). At 10 μM, GSK-4112 can reset the circadian rhythm in a phasic manner by inhibiting expression of the circadian target gene bmal1 and reduce glucose output by 30% in mouse primary hepatocytes by repressing the expression of several glucone

Question 4

Is there an additional fee for hazardous or dry ice shipping of this product?

Accepted Answer

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

Question 5

How many freeze-thaw cycles can this product tolerate?

Accepted Answer

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Question 6

Is antigen retrieval required for IHC with this antibody?

Accepted Answer

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

GSK-4112

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