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Stat5 Inhibitor

STAT5 Inhibitor suppresses STAT5 by targeting its SH2 domain (IC₅₀ = 47 µM against STAT5β SH2 domain EPO peptide binding activity). Comparatively, this compound displays reduced potency towards inhibiting the SH2 domain of STAT1, STAT3, or Lck (IC₅₀ > 500 µM). STAT5 Inhibitor has been shown to block STAT5/STAT5 DNA binding in K562 nuclear extracts. Cell-permeable.

Product Specifications

Shipping Conditions

Gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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