Rigosertib
Rigosertib is a potent, specific PLK1 (Polo -Like Kinase 1) inhibitor (IC₅₀ = 9 nM). Rigosertib strongly inhibits the proliferation of cancer cell lines, with observed IC₅₀ values in the nanomolar range for both HeLa (115 nM) and C33A (45 nM) cells. In contrast, Rigosertib has a minimal effect on normal cell lines, BJ and Ect1/E6E7 (IC₅₀ > 0.1 mM).
Product Specifications
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
36 months
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