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MDV-3100

MDV-3100 (Enzalutamide) is an androgen-receptor (AR) antagonist (IC₅₀ = 36 nM). Prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.

Product Specifications

Shipping Conditions

Gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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