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LY-2157299

LY-2157299 is a potent and selective TGFβ receptor I (TβRI) inhibitor (IC₅₀ = 56 nM). LY-2157299 abolishes the TGFβ induced Smad2 phosphorylation in HUVEC cells. It also shows dose dependent potentiation of VEGF or bFGF induced cell proliferation in HUVEC.

Product Specifications

Shipping Conditions

Gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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