GSK-2606414
GSK-2606414 is a potent and selective inhibitor of protein kinase R-like ER kinase (PERK) with IC₅₀ value of 0.4 nM. Displays >1000-fold selectivity for PERK over HR1 and PKR. GSK-2606414 inhibits PERK activation in cells and inhibits the growth of a human tumor xenograft in mice.
Product Specifications
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
36 months
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