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IOX2

IOX-2 is a potent, cell-permeable and selective inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC₅₀ = 21 nM). It displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3.

Product Specifications

Shipping Conditions

Gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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