Tenovin-1
Tenovin-1 is a small molecule p53 activator that protects against MDM2-mediated p53 degradation. It acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months
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