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Tenovin-1

Tenovin-1 is a small molecule p53 activator that protects against MDM2-mediated p53 degradation.  It acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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