Nourseothricin sulfate

Nourseothricin is group of a broad-spectrum antibiotic produced by Streptomyces variants; inhibits protein synthesis by inducing miscoding. Streptothricin antibiotic Nourseothricin (NTC) is used for a broad spectrum of viruses, bacteria and other unicellular or complex organisms. Preferred selection antibiotic for genetically modified Gram-positive and Gram-negative bacteria, yeast, filamentous fungi, protozoa, plants and many more. Selection of recombinant strains is based on inactivation of NTC by monoacetylation of ß-amino group of the ß-lysine by Nouresothricin N-acetyltransferase, the product of the sat1 gene.