2,6-Dithiopurine

2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis[1].

Product Specifications

CAS Number

[5437-25-2]

Product Name Alternative

2,6-Dimercaptopurine

UNSPSC

12352005

Hazard Statement

H317, H319

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-6-dithiopurine.html

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

S=C(N1)NC2=C(N=CN2)C1=S

Molecular Formula

C5H4N4S2

Molecular Weight

184.25

Precautions

H317, H319

References & Citations

[1]Stephen Boulware, et al. 2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2- (chloroethyl) ethyl sulfide, a mustard gas analog. Toxicol Appl Pharmacol. 2012 Sep 1;263 (2) :203-9.|[2]Stephen Boulware, et al. 2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2- (chloroethyl) ethyl sulfide, a mustard gas analog. Toxicol Appl Pharmacol. 2012 Sep 1;263 (2) :203-9.