Antipain dihydrochloride

Antipain is a reversible protease inhibitor that inhibits cathepsin A, B, and D as well as papain, trypsin and trypsin-like serine proteases. Antipain is more specific for papain and trypsin than is leupeptin (Cat. No. 1648). The inhibitory potency of antipain is 100-fold higher than that of elastatinal. Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase.