PF-573228
PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM. Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months
More Discoveries
Explore Other Products
Browse additional items from our catalog
A11269-10mM-D 10 mM x 1mL in DMSO
IPI-504 (Retaspimycin HCl) 10mM * 1mL in DMSO
Sign In for Pricing
View Details 
7-04100 3 µg
Recombinant Protein Kinase A Inactive holoenzyme type 2 alpha
Sign In for Pricing
View Details