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HA-CD44 interaction inhibitor 1

HA-CD44 interaction inhibitor 1 (compound 6) is an inhibitor of hyaluronic acid targeting to CD44, as well as an anti-tumor agent. Hyaluronic acid interacts with differentiation cluster 44 (CD44) and is involved in tumor growth and invasion. HA-CD44 interaction inhibitor 1 inhibits MDA-MB-231 cells with EC50 value of 1.77 μM[1].

Product Specifications

CAS Number

3052354-70-5

UNSPSC

12352005

Target

Transmembrane Glycoprotein

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ha-cd44-interaction-inhibitor-1.html

Purity

99.34

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

COC1=C(OC)C(OC)=CC(CN2CC3=C(C(Br)=CC=C3)CC2)=C1

Molecular Formula

C19H22BrNO3

Molecular Weight

392.29

References & Citations

[1]Espejo-Román JM, et al. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Eur J Med Chem. 2023 Oct 5;258:115570.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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