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VX-745

VX-745 is a potent and selective inhibitor of p38α (IC₅₀ = 10 nM). It displays 22-fold greater selectivity versus p38β and no inhibition of p38γ. Also blocks TNFα production in LPS-stimulated HWB in vitro (IC₅₀ = 177 nM).

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20°C

Shelf Life

36 months

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