Question 1

What is the catalog number for GSK-2118436 mesylate?

Accepted Answer

The catalog number for GSK-2118436 mesylate is 2800-5.

Question 2

Is GSK-2118436 mesylate in stock?

Accepted Answer

GSK-2118436 mesylate is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is GSK-2118436 mesylate used for?

Accepted Answer

GSK2118436 is a selective BRAF V600E inhibitor. GSK2118436 binds to Raf family kinases and inhibits their activity. It is highly selective against B-Raf V600E with IC₅₀ of 0.8 nM, compared to wild type B-Raf and c-Raf with IC₅₀s of 3.2 nM and 5.0 nM, respectively.

Question 4

Is there an additional fee for hazardous or dry ice shipping of this product?

Accepted Answer

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

Question 5

How many freeze-thaw cycles can this product tolerate?

Accepted Answer

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Question 6

Is antigen retrieval required for IHC with this antibody?

Accepted Answer

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

GSK-2118436 mesylate

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