Question 1

What is the catalog number for Picropodophyllotoxin?

Accepted Answer

The catalog number for Picropodophyllotoxin is 2765-1.

Question 2

Is Picropodophyllotoxin in stock?

Accepted Answer

Picropodophyllotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is Picropodophyllotoxin used for?

Accepted Answer

A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC₅₀ ~ 1 nM. Displays antiproliferative activity in numerous tumor cell lines, IC₅₀ = 0.05 - 15 mM.

Question 4

Is this product species cross-reactive?

Accepted Answer

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Question 5

Is there an additional fee for hazardous or dry ice shipping of this product?

Accepted Answer

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

Question 6

How many freeze-thaw cycles can this product tolerate?

Accepted Answer

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Picropodophyllotoxin

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