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Filipin III

Filipin III is a polyene macrolide antibiotic isolated from Streptomyces filipinensis. It may be used in a double staining procedure for the detection of lipoproteins. Binds specifically to cholesterol forming a fluorescent complex which may be used for staining. Filipin III disrupts the lipid raft/caveolae endocytosis pathway. Prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20°C

Shelf Life

36 months

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