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PF299804

PF299804 (Dacomitinib) is a potent, irreversible pan-HER inhibitor with IC₅₀’s of 6, 46, and 74 nM for ErbB1(HER1), ErbB2 (HER2), and ErbB4 (HER4), respectively. PF299804 inhibits ErbB1 autophosphorylation in A431 cells with an IC₅₀ of 15 nM.

Product Specifications

Shipping Conditions

Gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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