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EZSolution™ GW2580

A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases.  GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

12 months

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