Question 1

What is the catalog number for ETP-46464?

Accepted Answer

The catalog number for ETP-46464 is 2457-5.

Question 2

Is ETP-46464 in stock?

Accepted Answer

ETP-46464 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is ETP-46464 used for?

Accepted Answer

A potent ATR (ATM and Rad3-related) inhibitor (IC₅₀ = 25 nM). It also inhibits the activity of PI3Kα, mTOR and DNA-PKC with IC₅₀'s of 170, 0.6 and 36 nM, respectively. ETP-46464 inhibits the restart of stalled replication forks and abrogates S phase arrest after exposure to hydroxyurea.

Question 4

What is the recommended storage temperature after reconstitution?

Accepted Answer

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Question 5

Can this product be used in multiplex assays?

Accepted Answer

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

Question 6

What happens if this product doesn’t perform as expected in my experiment?

Accepted Answer

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

ETP-46464

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