RNF146, Human (His)

RNF146 protein is an E3 ubiquitin protein ligase that specifically recognizes and binds poly-ADP-ribosylated (PARsylated) proteins and coordinates their ubiquitination and degradation. Its critical roles span cell survival, DNA damage response, and activation of Wnt signaling. RNF146 Protein, Human (His) is the recombinant human-derived RNF146 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RNF146 Protein, Human (His) is 358 a.a., .