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GW-5074

Cell-permeable. A potent inhibitor of cRAF1 kinase (IC₅₀ = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects in vivo via a mechanism that is independent of MEK, ERK, and Akt signaling.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20 ̊C

Shelf Life

36 months

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