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EPZ-6438

A potent and selective inhibitor of histone methyltransferase EZH2. EPZ-6438 specifically inhibits cellular H3K27 methylation leading to selective apoptotic killing of SMARCB1 mutant MRT cells. It also induces neuronal differentiation and cell cycle inhibition while suppressing expression of Hedgehog (Hh) pathway genes.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20 ̊C

Shelf Life

36 months

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