DTSSP Crosslinker

KEY FEATURES & APPLICATIONS: • Water-soluble • Has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends • Contains cleavable, 8-atom (12 Å) spacer arm • The disulfide bond in the spacer arm is cleavable with reducing agents such as DTT, TCEP, etc. • DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins