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Tranylcypromine (hemisulfate) (Standard)

Tranylcypromine (hemisulfate) (Standard) is the analytical standard of Tranylcypromine (hemisulfate) . This product is intended for research and analytical applications. Tranylcypromine (SKF 385) hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hemisulfate is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Tranylcypromine has antidepressant effects[1][2].

Product Specifications

CAS Number

13492-01-8

Product Name Alternative

SKF 385 (hemisulfate) (Standard)

UNSPSC

12352005

Target

Histone Demethylase; Monoamine Oxidase; Reference Standards

Type

Reference Standards

Related Pathways

Epigenetics; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tranylcypromine-hemisulfate-standard.html

Smiles

N[C@H]1[C@H](C2=CC=CC=C2)C1.[0.5H2SO4]

Molecular Formula

C9H12NO2S0.5

Molecular Weight

182.23

References & Citations

[1]Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ (1-42) -induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.|[2]Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.|[3]Tsutsumi T, et al. Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity. Invest Ophthalmol Vis Sci. 2016 Nov 1;57 (14) :6461-6473.|[4]Romanczyk TB, et al. The antidepressant tranylcypromine alters cellular proliferation and migration in the adult goldfish brain. Anat Rec (Hoboken) . 2014 Oct;297 (10) :1919-26.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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