GSK343
A potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC₅₀ = 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC₅₀ of <200nM (measured by immunofluorescence).
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months
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