Question 1

What is the catalog number for Smo Antagonist, SA10?

Accepted Answer

The catalog number for Smo Antagonist, SA10 is 2159-5.

Question 2

Is Smo Antagonist, SA10 in stock?

Accepted Answer

Smo Antagonist, SA10 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is Smo Antagonist, SA10 used for?

Accepted Answer

SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC₅₀ = 5 µM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the β-galactosidase act

Question 4

Can this product be used for co-immunoprecipitation (Co-IP)?

Accepted Answer

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Question 5

Is this kit compatible with automated liquid handling platforms?

Accepted Answer

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

Question 6

What applications has this product been validated for?

Accepted Answer

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

Smo Antagonist, SA10

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