Nigericin sodium salt
Nigericin is a polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K⁺> Rb⁺ Cs⁺>> Na⁺. Also activates NLRP3/NALP3 and signals through pannexin-1 to induce caspase-1 maturation and IL-1β processing and release.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24months
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