Digitonin, Water-Soluble

Digitonin is a steroid glycoside from Digitalis purpurea. It belongs to the class of non-ionic detergents commonly used for solubilization of membrane proteins and permeabilization cellular and nuclear membranes. It permeabilizes plasma membranes of eukaryotic cells by complexing with membrane cholesterol and other unconjugated β-hydroxysterols.